In today’s business world, being personally connected is critical. We understand that “who” is as important as “what” in knowing where to turn to get things done. Discover how CORTEX connects the dots.


The CORTEX District (Center of Research, Technology and Entrepreneurial Exchange) is being planned as a knowledge community, a lively setting for work, play and living. It will encompass far more than laboratories and offices for research. In contrast to past models of research parks as isolated suburban enclaves, a knowledge community is designed to become an urban neighborhood full of 24/7 activity. Housing, retail, hotels, open spaces and public amenities are all part of the development to attract young entrepreneurs and small companies in addition to seasoned scientists, corporate executives and local residents.

Architecturally, the research buildings of knowledge communities are open and dynamic to reveal the innovations taking place inside. Existing structures can be retrofitted with flex/cool space – open, unstructured work areas – to support unconventional workplace arrangements. Ground-floor spaces support retail, restaurants, cafes and “street science” – visible work places exposing scientific and research activities to passersby.

The CORTEX district is centrally located on several hundred acres in the heart of the Midwest, St. Louis, Missouri. Founded by several iconic St. Louis universities, the district has thrived since its beginning and, with Phase II, is primed to continue its national significance as a scientific hub of activity for both large and small companies and research firms.

Tenants include Pfizer, DuPont Nutrition & Health, Washington University Genome Center, Washington University School of Medicine, St. Louis University Hospital, St. Louis College of Pharmacy, and Barnes-Jewish Hospital, to name just a few.

CORTEX also connects tenants with local scientific and business resources including:

Learn more about CORTEX here.

The CORTEX Master Plan includes transportation solutions such as highway access, a light rail station, and even bicycle exchanges to allow easy navigation throughout the CORTEX Campus. Sustainability is another key focus with features that will utilize low-impact development techniques (LID) to manage water runoff as close to the source as possible. Plantings and vegetation in green spaces surrounding buildings will incorporate native species and provide pleasant green spaces amid the urban infrastructure.

The Neighborhood

The intent of the CORTEX Master Plan is to create well-designed public open spaces that will contribute significantly to the quality of life within the district, community and city. The Master Plan calls for the creation of the CORTEX Commons, a public park that will be accessible to all who work and live in the district and surrounding neighborhoods.

The Commons: right in front of the @4240 entrance you’ll find a beautiful green space with areas for relaxing, meeting, or just enjoying the fresh air.

Restaurants/Cafes: surrounding the @4240 building will be cafes, restaurants and other places to grab lunch, dinner, or have cocktails after work.

Living Space: within walking distance of @4240 are lofts, apartments and other living spaces that allow for a commute that is literally minutes away.

Shops: retail space will be part of the new Phase II expansion, providing convenient shopping and unique boutiques all within a short stroll of the office and laboratory space.

Transportation: getting to and from work will be simplified for those driving as well as those wishing to use public transportation. A new highway interchange at the major east-west Interstate 64 provides convenient access for drivers, plus a new MetroLink light rail station will be within a block of the @4240 building.

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